Target Information
Target General Infomation | |||||
---|---|---|---|---|---|
Target ID |
T05387
|
||||
Former ID |
TTDC00120
|
||||
Target Name |
Protein-glutamine gamma-glutamyltransferase
|
||||
Gene Name |
TGM2
|
||||
Synonyms |
TG(C); TG(C)Protein-glutamine gamma-glutamyltransferase; TGC; TGase C; TGase-H; TTg; Tissue transglutaminase; Tranglutaminase 2; Transglutaminase 2; TGM2
|
||||
Target Type |
Research
|
||||
Function |
Catalyzes the cross-linking of proteins and the conjugation of polyamines to proteins.
|
||||
BioChemical Class |
Acyltransferase
|
||||
Target Validation |
T05387
|
||||
UniProt ID | |||||
EC Number |
EC 2.3.2.13
|
||||
Sequence |
MAEELVLERCDLELETNGRDHHTADLCREKLVVRRGQPFWLTLHFEGRNYEASVDSLTFS
VVTGPAPSQEAGTKARFPLRDAVEEGDWTATVVDQQDCTLSLQLTTPANAPIGLYRLSLE ASTGYQGSSFVLGHFILLFNAWCPADAVYLDSEEERQEYVLTQQGFIYQGSAKFIKNIPW NFGQFEDGILDICLILLDVNPKFLKNAGRDCSRRSSPVYVGRVVSGMVNCNDDQGVLLGR WDNNYGDGVSPMSWIGSVDILRRWKNHGCQRVKYGQCWVFAAVACTVLRCLGIPTRVVTN YNSAHDQNSNLLIEYFRNEFGEIQGDKSEMIWNFHCWVESWMTRPDLQPGYEGWQALDPT PQEKSEGTYCCGPVPVRAIKEGDLSTKYDAPFVFAEVNADVVDWIQQDDGSVHKSINRSL IVGLKISTKSVGRDEREDITHTYKYPEGSSEEREAFTRANHLNKLAEKEETGMAMRIRVG QSMNMGSDFDVFAHITNNTAEEYVCRLLLCARTVSYNGILGPECGTKYLLNLNLEPFSEK SVPLCILYEKYRDCLTESNLIKVRALLVEPVINSYLLAERDLYLENPEIKIRILGEPKQK RKLVAEVSLQNPLPVALEGCTFTVEGAGLTEEQKTVEIPDPVEAGEEVKVRMDLLPLHMG LHKLVVNFESDKLKAVKGFRNVIIGPA |
||||
Structure |
1FAU; 1KV3; 2Q3Z; 3LY6; 3S3J; 3S3P; 3S3S
|
||||
Pathways | |||||
KEGG Pathway | Huntington' | ||||
s disease | |||||
Pathway Interaction Database | Beta1 integrin cell surface interactions | ||||
Thromboxane A2 receptor signaling | |||||
Alpha9 beta1 integrin signaling events | |||||
References |
If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Zhou and Dr. Zhang.