Target General Infomation
Target ID
T51284
Former ID
TTDR00655
Target Name
Pyridoxal phosphate biosynthetic protein pdxJ
Gene Name
pdxJ
Synonyms
PNP synthase; Pyridoxine 5'-phosphate synthase; pdxJ
Target Type
Research
Function
Catalyzes the condensation of 1-deoxy-d-xylulose-5- phosphate (dxp) and 1-amino-3-(phosphohydroxy)propan-2-one to form pyridoxine 5'-phosphate (pnp).
UniProt ID
Sequence
MAELLLGVNIDHIATLRNARGTAYPDPVQAAFIAEQAGADGITVHLREDRRHITDRDVRI
LRQTLDTRMNLEMAVTEEMLAIAVETKPHFCCLVPEKRQEVTTEGGLDVAGQRDKMRDAC
KRLADAGIQVSLFIDADEEQIKAAAEVGAPFIEIHTGCYADAKTDAEQAQELARIAKAAT
FAASLGLKVNAGHGLTYHNVKAIAAIPEMHELNIGHAIIGRAVMTGLKDAVAEMKRLMLE
ARG
Inhibitor 1-Deoxy-D-Xylulose-5-Phosphate Drug Info [551393]
3-Phosphoglycerol Drug Info [551393]
Pyridoxine-5'-Phosphate Drug Info [551393]
References
Ref 551393How many drug targets are there? Nat Rev Drug Discov. 2006 Dec;5(12):993-6.

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