Drug General Information
Drug ID
D02XKE
Former ID
DIB018512
Drug Name
1-oleoyl glycerol
Drug Type
Small molecular drug
Indication Discovery agent Investigative [541090]
Structure
Download
2D MOL
Formula
C21H40O4
InChI
InChI=1S/C21H40O4/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-21(24)25-19-20(23)18-22/h9-10,20,22-23H,2-8,11-19H2,1H3/b10-9-
InChIKey
RZRNAYUHWVFMIP-KTKRTIGZSA-N
PubChem Compound ID
PubChem Substance ID
Target and Pathway
Target(s) Glucose-dependent insulinotropic receptor Target Info Agonist [531569]
KEGG Pathway cAMP signaling pathway
Insulin secretion
WikiPathways Incretin Synthesis, Secretion, and Inactivation
References
Ref 541090(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 5756).
Ref 5315692-Oleoyl glycerol is a GPR119 agonist and signals GLP-1 release in humans. J Clin Endocrinol Metab. 2011 Sep;96(9):E1409-17.

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