Drug General Information
Drug ID	D0M7NA
Former ID	DCL000026
Drug Name	A-993610
Indication	Pain [ICD9: 338, 356.0, 356.8,780; ICD10:G64, G90.0, R52, G89]		Investigative	[531236]
Therapeutic Class	Analgesics
Company	Abbott
Structure		Download 2D MOL 3D MOL
Target and Pathway
Target(s)	Vanilloid receptor 1	Target Info	Blocker	[537396]
KEGG Pathway	Neuroactive ligand-receptor interaction
	Inflammatory mediator regulation of TRP channels
NetPath Pathway	IL2 Signaling Pathway
Pathway Interaction Database	Trk receptor signaling mediated by the MAPK pathway
	Trk receptor signaling mediated by PI3K and PLC-gamma
Reactome	TRP channels
References
Ref 531236	TRPV1 receptor blockade is ineffective in different in vivo models of migraine. Cephalalgia. 2011 Jan;31(2):172-80.
Ref 537396	Analgesic potential of TRPV1 antagonists. Biochem Pharmacol. 2009 Aug 1;78(3):211-6. Epub 2009 Mar 5.

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