TTD | Drug: D0M3LK

Drug General Information
Drug ID	D0M3LK
Former ID	DIB018990
Drug Name	BMS270394
Synonyms	BMS 961; BMS-270394; BMS 270394
Drug Type	Small molecular drug
Indication	Discovery agent		Investigative	[539720]
Structure		Download 2D MOL
Formula	C23H26FNO4
InChI	InChI=1S/C23H26FNO4/c1-22(2)9-10-23(3,4)16-11-13(5-7-15(16)22)19(26)20(27)25-18-8-6-14(21(28)29)12-17(18)24/h5-8,11-12,19,26H,9-10H2,1-4H3,(H,25,27)(H,28,29)/t19-/m1/s1
InChIKey	AANFHDFOMFRLLR-LJQANCHMSA-N
PubChem Compound ID	445455
PubChem Substance ID	838632, 7885242, 10299698, 14903576, 14928147, 36888163, 53790867, 80274845, 85240515, 99443502, 104634335, 135650002, 135697732, 143196412, 160968116, 226527888, 246778948, 252159927
Target and Pathway
Target(s)	Retinoic acid receptor gamma	Target Info	Agonist	[525782]
Reactome	Nuclear Receptor transcription pathway
WikiPathways	Vitamin A and Carotenoid Metabolism
	Nuclear Receptors in Lipid Metabolism and Toxicity
	Mesodermal Commitment Pathway
	Endoderm Differentiation
	Nuclear Receptors
References
Ref 539720	(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 2653).
Ref 525782	Enantiomer discrimination illustrated by high-resolution crystal structures of the human nuclear receptor hRARgamma. Proc Natl Acad Sci U S A. 2000 Jun 6;97(12):6322-7.

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Drug Information