Drug Information

Drug General Information
Drug ID
D06CDW
Former ID
DIB020749
Drug Name
PPAHV
Synonyms
phorbol-12-phenylacetate-13-acetate-20-homovanillate
Drug Type
Small molecular drug
Indication Discovery agent Investigative [539615]
Structure
Download
2D MOL
Formula
C39H44O11
InChI
InChI=1S/C39H44O11/c1-21-14-30-37(45,34(21)44)19-26(20-48-31(42)18-25-12-13-28(41)29(16-25)47-6)15-27-33-36(4,5)39(33,50-23(3)40)35(22(2)38(27,30)46)49-32(43)17-24-10-8-7-9-11-24/h7-16,22,27,30,33,35,41,45-46H,17-20H2,1-6H3/t22-,27+,30-,33-,35-,37-,38-,39-/m1/s1
InChIKey
OGRGWTXWAZBJKF-JXWJAAHMSA-N
PubChem Compound ID
3035862
PubChem Substance ID
10048455, 15014139, 26755765, 36079230, 53787854, 53801086, 57353278, 75915696, 99030022, 103325289, 103949312, 111639948, 124892385, 135083052, 162227762, 241182453, 241375450
Target and Pathway
Target(s) Vanilloid receptor 1 Target Info Activator [525987]
KEGG Pathway Neuroactive ligand-receptor interaction
Inflammatory mediator regulation of TRP channels
NetPath Pathway IL2 Signaling Pathway
Pathway Interaction Database Trk receptor signaling mediated by the MAPK pathway
Trk receptor signaling mediated by PI3K and PLC-gamma
Reactome TRP channels
References
Ref 539615(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 2490).
Ref 525987Pharmacological differences between the human and rat vanilloid receptor 1 (VR1). Br J Pharmacol. 2001 Mar;132(5):1084-94.

If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Zhou and Dr. Zhang.