Drug Information

Drug General Information
Drug ID
D02ZJI
Former ID
DNC000873
Drug Name
Levalbuterol
Drug Type
Small molecular drug
Indication Asthma [ICD10:J45] Approved [545941], [551871]
Structure
Download
2D MOL

3D MOL
Formula
C13H21NO3
Canonical SMILES
CC(C)(C)NCC(C1=CC(=C(C=C1)O)CO)O
InChI
1S/C13H21NO3/c1-13(2,3)14-7-12(17)9-4-5-11(16)10(6-9)8-15/h4-6,12,14-17H,7-8H2,1-3H3/t12-/m0/s1
InChIKey
NDAUXUAQIAJITI-LBPRGKRZSA-N
CAS Number
CAS 149234-08-2
PubChem Compound ID
123600
PubChem Substance ID
13934, 10240794, 10852016, 11111805, 11111806, 11112645, 11113612, 14798337, 26744252, 29303834, 49879812, 50071332, 57340474, 77876163, 93166666, 96024814, 99036159, 99234398, 99774850, 103266935, 103911314, 104418876, 117814444, 124881447, 125325478, 126524239, 126670038, 128684762, 131311264, 131835145, 135078939, 135376066, 136965309, 137001318, 139121247, 164795671, 175267044, 175269554, 177748808, 179150348, 184546277, 223519271, 223668238, 223982365, 226396078, 252091683, 252166097
ChEBI ID
ChEBI:8746
SuperDrug ATC ID
R03AC02
SuperDrug CAS ID
cas=018559949
Target and Pathway
Target(s) Beta-2 adrenergic receptor Target Info Antagonist [537409]
KEGG Pathway Calcium signaling pathway
cGMP-PKG signaling pathway
cAMP signaling pathway
Neuroactive ligand-receptor interaction
Endocytosis
Adrenergic signaling in cardiomyocytes
Salivary secretion
NetPath Pathway TCR Signaling Pathway
PANTHER Pathway Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway
Beta2 adrenergic receptor signaling pathway
Pathway Interaction Database Arf6 trafficking events
Arf6 signaling events
Reactome Adrenoceptors
G alpha (s) signalling events
WikiPathways Monoamine GPCRs
Calcium Regulation in the Cardiac Cell
GPCRs, Class A Rhodopsin-like
Vitamin D Receptor Pathway
GPCR ligand binding
GPCR downstream signaling
GPCRs, Other
References
Ref 545941Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800005434)
Ref 551871Drugs@FDA. U.S. Food and Drug Administration. U.S. Department of Health & Human Services. 2015
Ref 537409Beta-blockers in the treatment of hypertension: are there clinically relevant differences? Postgrad Med. 2009 May;121(3):90-8.

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