Drug Information

Drug General Information
Drug ID
D0G3RZ
Former ID
DNC010223
Drug Name
6-(4-Methylpiperazin-1-yl)-9H-purin-2-amine
Drug Type
Small molecular drug
Indication Discovery agent Investigative [530400]
Structure
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2D MOL

3D MOL
Formula
C10H15N7
Canonical SMILES
CN1CCN(CC1)C2=NC(=NC3=C2NC=N3)N
InChI
1S/C10H15N7/c1-16-2-4-17(5-3-16)9-7-8(13-6-12-7)14-10(11)15-9/h6H,2-5H2,1H3,(H3,11,12,13,14,15)
InChIKey
HZZXEPZFOVOWIN-UHFFFAOYSA-N
PubChem Compound ID
46228161
Target and Pathway
Target(s) Histamine H4 receptor Target Info Inhibitor [530400]
KEGG Pathway Neuroactive ligand-receptor interaction
Reactome Histamine receptors
G alpha (i) signalling events
WikiPathways GPCR ligand binding
GPCR downstream signaling
GPCRs, Other
References
Ref 530400Bioorg Med Chem. 2009 Oct 15;17(20):7186-96. Epub 2009 Sep 2.2,4-Diaminopyrimidines as histamine H4 receptor ligands--Scaffold optimization and pharmacological characterization.
Ref 530400Bioorg Med Chem. 2009 Oct 15;17(20):7186-96. Epub 2009 Sep 2.2,4-Diaminopyrimidines as histamine H4 receptor ligands--Scaffold optimization and pharmacological characterization.

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