Drug Information
Drug General Information | |||||
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Drug ID |
D05PYO
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Former ID |
DIB018902
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Drug Name |
aspirin-triggered resolvin D1
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Synonyms |
AT-Resolvin D1; AT-RvD1
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Drug Type |
Small molecular drug
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Indication | Discovery agent | Investigative | [541408] | ||
Structure |
Download2D MOL |
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Formula |
C22H32O5
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InChI |
InChI=1S/C22H32O5/c1-2-3-9-14-19(23)15-10-6-4-5-7-11-16-20(24)21(25)17-12-8-13-18-22(26)27/h3-12,15-16,19-21,23-25H,2,13-14,17-18H2,1H3,(H,26,27)/b6-4-,7-5+,9-3-,12-8-,15-10+,16-11+/t19-,20-,21+/m1/s1
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InChIKey |
OIWTWACQMDFHJG-BJEBZIPWSA-N
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PubChem Compound ID | |||||
PubChem Substance ID | |||||
Target and Pathway | |||||
Target(s) | FMLP-related receptor I | Target Info | Agonist | [531857] | |
Transient receptor potential cation channel subfamily V member 3 | Target Info | Blocker (channel blocker) | [531538] | ||
KEGG Pathway | Inflammatory mediator regulation of TRP channels | ||||
Pathway Interaction Database | Urokinase-type plasminogen activator (uPA) and uPAR-mediated signaling | ||||
References | |||||
Ref 531538 | 17(R)-resolvin D1 specifically inhibits transient receptor potential ion channel vanilloid 3 leading to peripheral antinociception. Br J Pharmacol. 2012 Feb;165(3):683-92. | ||||
Ref 531857 | Resolvin D1 receptor stereoselectivity and regulation of inflammation and proresolving microRNAs. Am J Pathol. 2012 May;180(5):2018-27. |
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