Drug General Information
Drug ID
D06IAR
Former ID
DAP000223
Drug Name
Adenosine
Synonyms
ADN; Adenocard; Adenocor; Adenoscan; Adenosin; Adensoine; Boniton; Myocol; Nucleocardyl; Pallacor;Polyadenosine; Polyriboadenosine; Sandesin; Vidarabine; Adenine nucleoside; Adenine riboside; Adenosin [German]; SR 96225; Ade-Rib; Adenocard (TN); Adenocard, Adenosine; Adenoscan (TN); Adenosine [USAN:BAN]; Adenosine, homopolymer; Beta-Adenosine; MEDR-640; SR-96225; SUN-Y4001; USAF CB-10; Adenine-D-ribose; Adenosine (JAN/USP); Beta-D-Adenosine; Adenine 9-beta-D-arabinofuranoside; Adenine-9-beta-D-ribofuranoside; Beta-D-Ribofuranoside, adenine-9; EA6C60C2-6AFB-4264-A2F0-541373DB950E; (2R,3R,4S,5R)-2-(6-Aminopurin-9-yl)-5-(hydroxymethyl)oxolane-3,4-diol; (2R,3R,4S,5R)-2-(6-amino-9H-purin-9-yl)-5-(hydroxymethyl)oxolane-3,4-diol; 4-Aminopyrazolo[3,4-d]pyrimidine ribonucleoside; 6-Amino-9-.beta.-ribofuranosyl-9H-purine; 6-Amino-9-beta-D-ribofuranosyl-9H-purine; 6-Amino-9beta-D-ribofuranosyl-9H-purine; 9-(beta-D-Arabinofuranosyl)adenine; 9-beta-D-Ribofuranosidoadenine; 9-beta-D-Ribofuranosyl-9H-purin-6-amine; 9-beta-D-Ribofuranosyladenine; 9beta-D-Ribofuranosyladenine
Drug Type
Small molecular drug
Indication Paroxysmal supraventricular tachycardia [ICD9: 427, 427.0, 427.1, 427.89, 785.0; ICD10:I47-I49, I47.1, I47.2, R00.0] Approved [536838], [539879]
Therapeutic Class
Antiarrhythmic Agents
Structure
Download
2D MOL

3D MOL

Formula
C10H13N5O4
InChI
InChI=1S/C10H13N5O4/c11-8-5-9(13-2-12-8)15(3-14-5)10-7(18)6(17)4(1-16)19-10/h2-4,6-7,10,16-18H,1H2,(H2,11,12,13)/t4-,6-,7-,10-/m1/s1
InChIKey
OIRDTQYFTABQOQ-KQYNXXCUSA-N
CAS Number
CAS 58-61-7
PubChem Compound ID
PubChem Substance ID
ChEBI ID
ChEBI:16335
SuperDrug ATC ID
C01EB10
SuperDrug CAS ID
cas=000058617
Target and Pathway
Target(s) Adenosine A2b receptor Target Info Modulator [556264]
KEGG Pathway Rap1 signaling pathway
Calcium signaling pathway
Neuroactive ligand-receptor interaction
Vascular smooth muscle contraction
Alcoholism
NetPath Pathway TGF_beta_Receptor Signaling Pathway
TCR Signaling Pathway
Pathway Interaction Database C-MYB transcription factor network
PathWhiz Pathway Intracellular Signalling Through Adenosine Receptor A2b and Adenosine
Reactome Adenosine P1 receptors
G alpha (s) signalling events
Surfactant metabolism
WikiPathways Nucleotide GPCRs
GPCRs, Class A Rhodopsin-like
GPCR ligand binding
GPCR downstream signaling
References
Ref 536838Emerging drugs for chemotherapy-induced mucositis. Expert Opin Emerg Drugs. 2008 Sep;13(3):511-22.
Ref 539879(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 2844).
Ref 556264Drugs@FDA. U.S. Food and Drug Administration. U.S. Department of Health & Human Services.

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