TTD | Drug: D0M7HH

Drug General Information
Drug ID	D0M7HH
Former ID	DIB018383
Drug Name	[3H]PSB-0413
Synonyms	[3H]AR-C67085; [3H]AR-C67085MX
Drug Type	Small molecular drug
Indication	Discovery agent		Investigative	[541342]
Structure		Download 2D MOL
Formula	C14H22Cl2N5O12P3S
InChI	InChI=1S/C14H22Cl2N5O12P3S/c1-2-3-37-13-19-10(17)7-11(20-13)21(5-18-7)12-9(23)8(22)6(32-12)4-31-36(29,30)33-35(27,28)14(15,16)34(24,25)26/h5-6,8-9,12,22-23H,2-4H2,1H3,(H,27,28)(H,29,30)(H2,17,19,20)(H2,24,25,26)/t6-,8-,9-,12-/m1/s1/i1T3,2T2
InChIKey	ZLIAJZQKKBOFJR-WNJXVAICSA-N
PubChem Compound ID	44405630
PubChem Substance ID	103474462, 104060933, 178102768
Target and Pathway
Target(s)	P2Y purinoceptor 12	Target Info	Antagonist	[527789]
KEGG Pathway	Platelet activation
Reactome	P2Y receptors
Reactome	G alpha (i) signalling events
WikiPathways	GPCRs, Class A Rhodopsin-like
	Signal amplification
	GPCR ligand binding
	GPCR downstream signaling
References
Ref 541342	(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 6147).
Ref 527789	Synthesis and preliminary evaluation of [3H]PSB-0413, a selective antagonist radioligand for platelet P2Y12 receptors. Bioorg Med Chem Lett. 2005 Dec 15;15(24):5450-2. Epub 2005 Oct 5.

If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Zhou and Dr. Zhang.

Drug Information