Drug General Information
Drug ID
D0M1FB
Former ID
DIB020566
Drug Name
N-palmitoylethanolamine
Synonyms
palmitoyl-EA; palmitamide MEA
Drug Type
Small molecular drug
Indication Discovery agent Investigative [540483]
Structure
Download
2D MOL
Formula
C18H37NO2
InChI
InChI=1S/C18H37NO2/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-18(21)19-16-17-20/h20H,2-17H2,1H3,(H,19,21)
InChIKey
HXYVTAGFYLMHSO-UHFFFAOYSA-N
PubChem Compound ID
PubChem Substance ID
Target and Pathway
Target(s) Glucose-dependent insulinotropic receptor Target Info Agonist [543393]
G-protein coupled receptor 55 Target Info Agonist [529051]
KEGG Pathway cAMP signaling pathway
Insulin secretion
Reactome Class A/1 (Rhodopsin-like receptors)
G alpha (i) signalling events
WikiPathways Incretin Synthesis, Secretion, and InactivationWP1825:GPCR ligand binding
GPCR downstream signaling
GPCRs, Other
References
Ref 540483(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 3622).
Ref 529051The orphan receptor GPR55 is a novel cannabinoid receptor. Br J Pharmacol. 2007 Dec;152(7):1092-101. Epub 2007 Sep 17.
Ref 543393(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 126).

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