Drug General Information
Drug ID	D0XR2J
Former ID	DNC014422
Drug Name	1-Amino-3-(aminoxy)-2-propanol Dihydrochloride
Drug Type	Small molecular drug
Indication	Discovery agent		Investigative	[531018]
Structure		Download 2D MOL 3D MOL
Formula	C3H11ClN2O2
Canonical SMILES	C(C(CON)O)N.Cl
InChI	1S/C3H10N2O2.ClH/c4-1-3(6)2-7-5;/h3,6H,1-2,4-5H2;1H
InChIKey	CDNYZQKHCXXBPH-UHFFFAOYSA-N
PubChem Compound ID	49862726
Target and Pathway
Target(s)	Ornithine decarboxylase	Target Info	Inhibitor	[531018]
BioCyc Pathway	Putrescine biosynthesis I
NetPath Pathway	TCR Signaling Pathway
	IL2 Signaling Pathway
	TGF_beta_Receptor Signaling Pathway
PANTHER Pathway	Ornithine degradation
	CCKR signaling map ST
Pathway Interaction Database	Validated targets of C-MYC transcriptional activation
PathWhiz Pathway	Spermidine and Spermine Biosynthesis
References
Ref 531018	Bioorg Med Chem Lett. 2010 Aug 1;20(15):4364-6. Epub 2010 Jun 17.Selective delivery of 2-hydroxy APA to Trypanosoma brucei using the melamine motif.
Ref 531018	Bioorg Med Chem Lett. 2010 Aug 1;20(15):4364-6. Epub 2010 Jun 17.Selective delivery of 2-hydroxy APA to Trypanosoma brucei using the melamine motif.

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