Drug Information

Drug General Information
Drug ID
D08HOK
Former ID
DIB019471
Drug Name
compound 3a
Drug Type
Small molecular drug
Indication Discovery agent Investigative [531413], [541072]
Structure
Download
2D MOL
Formula
C22H27N5O5S
InChI
InChI=1S/C22H27N5O5S/c1-22(2,3)32-21(28)26-11-9-16(10-12-26)31-20-18-13-25-27(19(18)23-14-24-20)15-5-7-17(8-6-15)33(4,29)30/h5-8,13-14,16H,9-12H2,1-4H3
InChIKey
LZCNLEZPKDPKSO-UHFFFAOYSA-N
PubChem Compound ID
11282871
PubChem Substance ID
16369811, 23454344, 42362312, 77790630, 127342717, 127342718, 127342719, 131276050, 131346383, 137218917, 139392265, 178102363, 223931643, 226718958, 246546231
Target and Pathway
Target(s) Glucose-dependent insulinotropic receptor Target Info Agonist [531413]
KEGG Pathway cAMP signaling pathway
Insulin secretion
WikiPathways Incretin Synthesis, Secretion, and Inactivation
References
Ref 531413Bioorg Med Chem Lett. 2011 May 15;21(10):3134-41. Epub 2011 Mar 13.Discovery of fused bicyclic agonists of the orphan G-protein coupled receptor GPR119 with in vivo activity in rodent models of glucose control.
Ref 541072(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 5737).
Ref 531413Bioorg Med Chem Lett. 2011 May 15;21(10):3134-41. Epub 2011 Mar 13.Discovery of fused bicyclic agonists of the orphan G-protein coupled receptor GPR119 with in vivo activity in rodent models of glucose control.

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