Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
D09QSY
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| Former ID |
DIB019879
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| Drug Name |
frescolat MGA
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| Synonyms |
menthone 1,2-glycerol ketal
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| Drug Type |
Small molecular drug
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| Indication | Discovery agent | Investigative | [1] | ||
| Structure |
|
Download2D MOL |
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| Formula |
C13H24O3
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| InChI |
InChI=1S/C13H24O3/c1-9(2)12-5-4-10(3)6-13(12)15-8-11(7-14)16-13/h9-12,14H,4-8H2,1-3H3
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| InChIKey |
ZBJCYZPANVLBRK-UHFFFAOYSA-N
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| PubChem Compound ID | |||||
| PubChem Substance ID |
10663145, 16630676, 46236904, 50564854, 53801001, 87245618, 103806153, 103806154, 113448882, 117603836, 118845689, 125355106, 126616290, 126685630, 129878294, 135116907, 137180186, 142639572, 152047925, 162886320, 163813729, 164810496, 172850455, 176260456, 184602918, 223677098, 226531299, 249625880, 252424228
|
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| Target and Pathway | |||||
| Target(s) | TRPM8 protein | Target Info | Activator | [2] | |
| KEGG Pathway | Inflammatory mediator regulation of TRP channels | ||||
| Reactome | TRP channels | ||||
| References | |||||
| REF 1 | (http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 2465). | ||||
| REF 2 | Characterization of the mouse cold-menthol receptor TRPM8 and vanilloid receptor type-1 VR1 using a fluorometric imaging plate reader (FLIPR) assay. Br J Pharmacol. 2004 Feb;141(4):737-45. Epub 2004Feb 2. | ||||
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