Drug Information

Drug General Information
Drug ID
D05FOV
Former ID
DIB018570
Drug Name
2-oleoyl glycerol
Synonyms
2-monoolein; 2-oleoyl-glycerol; 2-oleoylglycerol (2OG)
Drug Type
Small molecular drug
Indication Discovery agent Investigative [468176]
Structure
Download
2D MOL
Formula
C21H40O4
InChI
InChI=1S/C21H40O4/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-21(24)25-20(18-22)19-23/h9-10,20,22-23H,2-8,11-19H2,1H3/b10-9-
InChIKey
UPWGQKDVAURUGE-KTKRTIGZSA-N
PubChem Compound ID
5319879
PubChem Substance ID
11058082, 24896769, 39293560, 48418272, 48419757, 49663300, 49681178, 52150658, 57360667, 85257143, 99368391, 114174402, 123060563, 126530072, 134223603, 135266910, 144213851, 164174516, 164231759, 175270333, 178101805, 198966111, 226406387, 241075155, 242585213, 249914898, 252375510
Target and Pathway
Target(s) Glucose-dependent insulinotropic receptor Target Info Agonist [531569]
KEGG Pathway cAMP signaling pathway
Insulin secretion
WikiPathways Incretin Synthesis, Secretion, and Inactivation
References
Ref 468176(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 5112).
Ref 5315692-Oleoyl glycerol is a GPR119 agonist and signals GLP-1 release in humans. J Clin Endocrinol Metab. 2011 Sep;96(9):E1409-17.

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