Drug Information

Drug General Information
Drug ID
D0Y8EU
Former ID
DNC000961
Drug Name
MRS-1220
Drug Type
Small molecular drug
Indication Discovery agent Investigative [467723]
Structure
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2D MOL

3D MOL
Formula
C21H14ClN5O2
InChI
InChI=1S/C21H14ClN5O2/c22-14-8-9-16-15(12-14)20-25-19(17-7-4-10-29-17)26-27(20)21(23-16)24-18(28)11-13-5-2-1-3-6-13/h1-10,12H,11H2,(H,23,24,28)
InChIKey
TWWFAXQOKNBUCR-UHFFFAOYSA-N
PubChem Compound ID
393595
PubChem Substance ID
524902, 4962537, 7978522, 10280040, 11113966, 11438593, 14928432, 24896720, 26752111, 56459401, 57402361, 79893430, 85209185, 85788645, 91721454, 103295938, 103838465, 103950597, 104619372, 117467439, 129325621, 131306782, 135337698, 135650648, 135698354, 137054394, 142146734, 162022819, 162226562, 163124997, 184594867, 204366636, 208265240, 223468630, 227189785, 241182239, 241375304, 252215848
Target and Pathway
Target(s) Adenosine A3 receptor Target Info Antagonist [534925]
Reactome Adenosine P1 receptors
G alpha (i) signalling events
WikiPathways Nucleotide GPCRs
GPCRs, Class A Rhodopsin-like
GPCRs, Other
References
Ref 467723(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 448).
Ref 534925A(3) adenosine receptor activation attenuates neutrophil function and neutrophil-mediated reperfusion injury. Am J Physiol. 1999 Nov;277(5 Pt 2):H1895-905.

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