TTD | Drug: D0Q1HE

Drug General Information
Drug ID	D0Q1HE
Former ID	DIB020437
Drug Name	MRS2698
Synonyms	MRS-2698; 2'-amino-2-thio-UTP
Drug Type	Small molecular drug
Indication	Discovery agent		Investigative	[539085]
Structure		Download 2D MOL
Formula	C9H16N3O13P3S
InChI	InChI=1S/C9H16N3O13P3S/c10-6-7(14)4(23-8(6)12-2-1-5(13)11-9(12)29)3-22-27(18,19)25-28(20,21)24-26(15,16)17/h1-2,4,6-8,14H,3,10H2,(H,18,19)(H,20,21)(H,11,13,29)(H2,15,16,17)/t4-,6-,7-,8-/m1/s1
InChIKey	UWTUUIWWVPWHAA-XVFCMESISA-N
PubChem Compound ID	16116566
PubChem Substance ID	26682317, 40083935, 103509260, 135650664
Target and Pathway
Target(s)	P2Y purinoceptor 2	Target Info	Agonist	[528677]
KEGG Pathway	Neuroactive ligand-receptor interaction
KEGG Pathway	Inflammatory mediator regulation of TRP channels
NetPath Pathway	IL5 Signaling Pathway
Reactome	G alpha (q) signalling events
	P2Y receptors
	Surfactant metabolism
WikiPathways	Nucleotide GPCRs
	GPCRs, Class A Rhodopsin-like
	Gastrin-CREB signalling pathway via PKC and MAPK
	GPCR ligand binding
	GPCR downstream signaling
References
Ref 539085	(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 1733).
Ref 528677	Molecular modeling of the human P2Y2 receptor and design of a selective agonist, 2'-amino-2'-deoxy-2-thiouridine 5'-triphosphate. J Med Chem. 2007 Mar 22;50(6):1166-76. Epub 2007 Feb 16.

If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Zhou and Dr. Zhang.

Drug Information