TTD | Drug: D0T4FT

Drug General Information
Drug ID	D0T4FT
Former ID	DIB019541
Drug Name	compound 5a
Synonyms	Cbz-Leu-D,L-Phe-CONH-(CH(2))(3)-adenin-9-yl
Drug Type	Small molecular drug
Indication	Discovery agent		Investigative	[531089]
Structure		Download 2D MOL
Formula	C32H38N8O5
InChI	InChI=1S/C32H38N8O5/c1-21(2)16-25(39-32(44)45-18-23-12-7-4-8-13-23)30(42)38-24(17-22-10-5-3-6-11-22)27(41)31(43)34-14-9-15-40-20-37-26-28(33)35-19-36-29(26)40/h3-8,10-13,19-21,24-25H,9,14-18H2,1-2H3,(H,34,43)(H,38,42)(H,39,44)(H2,33,35,36)/t24?,25-/m0/s1
InChIKey	OVLNPOAZKHQAAD-BBMPLOMVSA-N
PubChem Compound ID	46930721
PubChem Substance ID	99436656, 120933644, 123097371, 123105419, 252166816
Target and Pathway
Target(s)	Calpain	Target Info	Inhibitor	[531089]
KEGG Pathway	Protein processing in endoplasmic reticulum
	Apoptosis
	Alzheimer's disease
Reactome	Degradation of the extracellular matrix
WikiPathways	Focal Adhesion
	Integrated Pancreatic Cancer Pathway
	Alzheimers Disease
	Integrin-mediated Cell Adhesion
References
Ref 531089	Peptidyl alpha-ketoamides with nucleobases, methylpiperazine, and dimethylaminoalkyl substituents as calpain inhibitors. J Med Chem. 2010 Sep 9;53(17):6326-36.
Ref 531089	Peptidyl alpha-ketoamides with nucleobases, methylpiperazine, and dimethylaminoalkyl substituents as calpain inhibitors. J Med Chem. 2010 Sep 9;53(17):6326-36.

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Drug Information