Drug Information
Drug General Information | |||||
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Drug ID |
D08NKJ
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Former ID |
DNC000709
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Drug Name |
Guanine
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Drug Type |
Small molecular drug
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Structure |
Download2D MOL |
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Formula |
C5H5N5O
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InChI |
InChI=1S/C5H5N5O/c6-5-9-3-2(4(11)10-5)7-1-8-3/h1H,(H4,6,7,8,9,10,11)
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InChIKey |
UYTPUPDQBNUYGX-UHFFFAOYSA-N
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CAS Number |
CAS 73-40-5
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PubChem Compound ID | |||||
PubChem Substance ID |
2779, 3541, 585679, 594396, 618937, 832638, 833698, 836921, 841460, 854934, 854953, 855322, 1433762, 3133367, 4491989, 4963597, 5161786, 6184055, 7004212, 7377195, 7644358, 7888029, 8022280, 8145637, 8150777, 10534208, 11416826, 14891624, 16020045, 16105542, 24277513, 24439126, 24697815, 24697817, 24697819, 24697820, 24697835, 24697922, 24895044, 24895050, 24895274, 25622131, 26683839, 26711837, 26712763, 26713089, 26717511, 26717514, 26750333, 26750346
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ChEBI ID |
ChEBI:16235
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Target and Pathway | |||||
Target(s) | GTP cyclohydrolase I | Target Info | Inhibitor | [535179] | |
PathWhiz Pathway | Pterine Biosynthesis | ||||
References | |||||
Ref 467793 | (http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 4556). | ||||
Ref 521421 | ClinicalTrials.gov (NCT00001100) A Phase III Study to Evaluate the Safety and Efficacy of Ganciclovir (Dihydroxypropoxymethyl Guanine [DHPG]) Treatment of Symptomatic Central Nervous System (CNS) Congenital Cytomegalovirus (CMV) Infections.. U.S. National Institutes of Health. |
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