Drug General Information
Drug ID
D01MOQ
Former ID
DNC003811
Drug Name
7-Methyl-2-propyl-[1,8]naphthyridin-4-ol
Drug Type
Small molecular drug
Indication Discovery agent Investigative [527090]
Structure
Download
2D MOL

3D MOL

Formula
C12H14N2O
Canonical SMILES
CCCC1=CC(=O)C2=C(N1)N=C(C=C2)C
InChI
1S/C12H14N2O/c1-3-4-9-7-11(15)10-6-5-8(2)13-12(10)14-9/h5-7H,3-4H2,1-2H3,(H,13,14,15)
InChIKey
JAFFZYFREVCDTP-UHFFFAOYSA-N
PubChem Compound ID
Target and Pathway
Target(s) Adenosine A1 receptor Target Info Inhibitor [527090]
KEGG Pathway cGMP-PKG signaling pathway
cAMP signaling pathway
Sphingolipid signaling pathway
Neuroactive ligand-receptor interaction
Morphine addiction
NetPath Pathway TCR Signaling Pathway
RANKL Signaling Pathway
PANTHER Pathway Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway
Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway
Reactome Adenosine P1 receptors
G alpha (i) signalling events
WikiPathways Nucleotide GPCRs
GPCRs, Class A Rhodopsin-like
GPCR ligand binding
GPCR downstream signaling
References
Ref 527090J Med Chem. 2004 Jun 3;47(12):3019-31.Study on affinity profile toward native human and bovine adenosine receptors of a series of 1,8-naphthyridine derivatives.
Ref 527090J Med Chem. 2004 Jun 3;47(12):3019-31.Study on affinity profile toward native human and bovine adenosine receptors of a series of 1,8-naphthyridine derivatives.

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