Drug Information

Drug General Information
Drug ID
D05EDD
Former ID
DIB021164
Drug Name
VPC23019
Synonyms
VPC 23019; VPC-23019
Drug Type
Small molecular drug
Indication Discovery agent Investigative [540284]
Structure
Download
2D MOL
Formula
C17H29N2O5P
InChI
InChI=1S/C17H29N2O5P/c1-2-3-4-5-6-7-9-14-10-8-11-15(12-14)19-17(20)16(18)13-24-25(21,22)23/h8,10-12,16H,2-7,9,13,18H2,1H3,(H,19,20)(H2,21,22,23)/t16-/m1/s1
InChIKey
MRUSUGVVWGNKFE-MRXNPFEDSA-N
PubChem Compound ID
11588811
PubChem Substance ID
16691322, 23703095, 42755655, 75559577, 103515373, 104079652, 137593398, 178100357, 196377565, 208265276, 237897647, 241376859, 245844563, 249618102, 252157863, 252450200, 252543730
Target and Pathway
Target(s) Sphingosine 1-phosphate receptor 1 Target Info Antagonist [527334]
Sphingosine-1-phosphate receptor-3 Target Info Antagonist [527334]
KEGG Pathway FoxO signaling pathway
Sphingolipid signaling pathway
Neuroactive ligand-receptor interactionhsa04071:Sphingolipid signaling pathway
Neuroactive ligand-receptor interaction
NetPath Pathway IL4 Signaling Pathway
TGF_beta_Receptor Signaling Pathway
IL2 Signaling Pathway
Pathway Interaction Database Fc-epsilon receptor I signaling in mast cells
S1P3 pathway
S1P1 pathway
Sphingosine 1-phosphate (S1P) pathway
PDGFR-beta signaling pathways1p_s1p3_pathway:S1P3 pathway
Reactome G alpha (i) signalling events
Lysosphingolipid and LPA receptorsR-HSA-418594:G alpha (i) signalling events
Lysosphingolipid and LPA receptors
WikiPathways Signal Transduction of S1P Receptor
Small Ligand GPCRs
GPCR ligand binding
GPCR downstream signaling
GPCRs, OtherWP26:Signal Transduction of S1P Receptor
References
Ref 540284(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 3324).
Ref 527334Sphingosine 1-phosphate analogs as receptor antagonists. J Biol Chem. 2005 Mar 18;280(11):9833-41. Epub 2004 Dec 8.

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