Drug Information

Drug General Information
Drug ID
D0T3NP
Former ID
DIB020338
Drug Name
methyl p-hydroxybenzoate
Synonyms
methylparaben; nipagin
Drug Type
Small molecular drug
Indication Discovery agent Investigative [541426]
Structure
Download
2D MOL
Formula
C8H8O3
InChI
InChI=1S/C8H8O3/c1-11-8(10)6-2-4-7(9)5-3-6/h2-5,9H,1H3
InChIKey
LXCFILQKKLGQFO-UHFFFAOYSA-N
PubChem Compound ID
7456
PubChem Substance ID
70258, 476047, 588052, 835422, 866372, 3133901, 3720853, 7639406, 7848463, 7889009, 8155032, 10539176, 14772312, 24871585, 24878967, 24878970, 24895585, 24895757, 24897298, 24901279, 25622945, 26754470, 29215301, 29226309, 48416256, 48417041, 48422035, 49887561, 50085960, 53776838, 53789381, 56369668, 57288789, 57324230, 57651483, 76300234, 81066216, 85087736, 85171246, 85279912, 87570645, 88520061, 93165693, 103329864, 104085945, 104315004, 104668333, 111677915, 124892120, 124892121
Target and Pathway
Target(s) Transient receptor potential cation channel subfamily A member 1 Target Info Activator [528726]
KEGG Pathway Inflammatory mediator regulation of TRP channels
Reactome TRP channels
References
Ref 541426(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 6273).
Ref 528726Methyl p-hydroxybenzoate causes pain sensation through activation of TRPA1 channels. Br J Pharmacol. 2007 May;151(1):153-60. Epub 2007 Mar 12.

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