Drug Information

Drug General Information
Drug ID
D07XEB
Former ID
DNC001032
Drug Name
Nonsteroidal anti-inflammatory drugs (NSAIDs)
Indication Discovery agent Investigative [535013]
Formula
C36H47NO10
Target and Pathway
Target(s) Arachidonate 15-lipoxygenase Target Info Inhibitor [535013]
BioCyc Pathway Resolvin D biosynthesis
Lipoxin biosynthesis
KEGG Pathway Arachidonic acid metabolism
Linoleic acid metabolism
Metabolic pathways
Serotonergic synapse
NetPath Pathway IL4 Signaling Pathway
PANTHER Pathway Inflammation mediated by chemokine and cytokine signaling pathway
Pathway Interaction Database IL4-mediated signaling events
PathWhiz Pathway Arachidonic Acid Metabolism
WikiPathways Arachidonic acid metabolism
Eicosanoid Synthesis
References
Ref 53501315-LOX-1: a novel molecular target of nonsteroidal anti-inflammatory drug-induced apoptosis in colorectal cancer cells. J Natl Cancer Inst. 2000 Jul 19;92(14):1136-42.
Ref 53501315-LOX-1: a novel molecular target of nonsteroidal anti-inflammatory drug-induced apoptosis in colorectal cancer cells. J Natl Cancer Inst. 2000 Jul 19;92(14):1136-42.

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