Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
D08TME
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| Former ID |
DNC006306
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| Drug Name |
2,5-bis(4-nitrophenyl)thiophene
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| Drug Type |
Small molecular drug
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| Indication | Discovery agent | Investigative | [527907] | ||
| Structure |
|
Download2D MOL |
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| Formula |
C16H10N2O4S
|
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| Canonical SMILES |
C1=CC(=CC=C1C2=CC=C(S2)C3=CC=C(C=C3)[N+](=O)[O-])[N+](=<br />O)[O-]
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| InChI |
1S/C16H10N2O4S/c19-17(20)13-5-1-11(2-6-13)15-9-10-16(23-15)12-3-7-14(8-4-12)18(21)22/h1-10H
|
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| InChIKey |
FBNOZEYGTWFASC-UHFFFAOYSA-N
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| PubChem Compound ID | |||||
| Target and Pathway | |||||
| Target(s) | Amyloid beta A4 protein | Target Info | Inhibitor | [527907] | |
| KEGG Pathway | Notch signaling pathway | ||||
| Alzheimer's disease | |||||
| Reactome | Nuclear signaling by ERBB4 | ||||
| Degradation of the extracellular matrix | |||||
| Regulated proteolysis of p75NTR | |||||
| NRIF signals cell death from the nucleus | |||||
| Activated NOTCH1 Transmits Signal to the Nucleus | |||||
| Constitutive Signaling by NOTCH1 PEST Domain Mutants | |||||
| Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants | |||||
| EPH-ephrin mediated repulsion of cells | |||||
| References | |||||
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