TTD | Drug: D0TM0N

Drug General Information
Drug ID	D0TM0N
Former ID	DIB021115
Drug Name	UCM 765
Synonyms	UCM-765; UCM765
Drug Type	Small molecular drug
Indication	Discovery agent		Investigative	[542842]
Structure		Download 2D MOL
Formula	C17H20N2O2
InChI	InChI=1S/C17H20N2O2/c1-14(20)18-12-13-19(15-6-4-3-5-7-15)16-8-10-17(21-2)11-9-16/h3-11H,12-13H2,1-2H3,(H,18,20)
InChIKey	PWTCGLHUMIIRML-UHFFFAOYSA-N
PubChem Compound ID	24749950
PubChem Substance ID	49652124, 56165376, 103541936, 229420378, 248495470, 249565606
Target and Pathway
Target(s)	Melatonin receptor	Target Info	Agonist	[529190]
KEGG Pathway	Neuroactive ligand-receptor interaction
KEGG Pathway	Circadian entrainment
Reactome	Class A/1 (Rhodopsin-like receptors)
Reactome	G alpha (i) signalling events
WikiPathways	GPCRs, Class A Rhodopsin-like
	Small Ligand GPCRs
	GPCR ligand binding
	GPCR downstream signaling
References
Ref 542842	(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 7923).
Ref 529190	N-(substituted-anilinoethyl)amides: design, synthesis, and pharmacological characterization of a new class of melatonin receptor ligands. J Med Chem. 2007 Dec 27;50(26):6618-26. Epub 2007 Dec 6.

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Drug Information