TTD | Drug: D0U4VW

Drug General Information
Drug ID	D0U4VW
Former ID	DIB019043
Drug Name	BX 048
Synonyms	BX-048; BX048
Drug Type	Small molecular drug
Indication	Discovery agent		Investigative	[539116]
Structure		Download 2D MOL
Formula	C27H34N4O9
InChI	InChI=1S/C27H34N4O9/c1-5-39-26(38)31-12-10-30(11-13-31)24(35)18(8-9-22(32)33)29-23(34)20-15-21(40-27(3,4)25(36)37)17-7-6-16(2)14-19(17)28-20/h6-7,14-15,18H,5,8-13H2,1-4H3,(H,29,34)(H,32,33)(H,36,37)
InChIKey	MCBLPJPMVOVJCO-UHFFFAOYSA-N
PubChem Compound ID	16741348
PubChem Substance ID	26719967, 38287984, 46573812, 135650044, 231235909, 245025073
Target and Pathway
Target(s)	P2Y purinoceptor 12	Target Info	Antagonist	[529525]
KEGG Pathway	Platelet activation
Reactome	P2Y receptors
Reactome	G alpha (i) signalling events
WikiPathways	GPCRs, Class A Rhodopsin-like
	Signal amplification
	GPCR ligand binding
	GPCR downstream signaling
References
Ref 539116	(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 1766).
Ref 529525	Novel P2Y12 adenosine diphosphate receptor antagonists for inhibition of platelet aggregation (II): pharmacodynamic and pharmacokinetic characterization. Thromb Res. 2008;122(4):533-40.

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Drug Information