Drug General Information
Drug ID
D04NXQ
Former ID
DAP001001
Drug Name
Pefloxacin
Synonyms
Abactal; Labocton; PERFLOXACIN; PFLX; Peflacine; Pefloxacine; Pefloxacino; Pefloxacinum; Pefloxacin methanesulfonate; Silver Pefloxacin; AM-725; EU-5306; Pefloxacin [INN-French]; Pefloxacino [INN-Spanish]; Pefloxacinum [INN-Latin]; Pefloxacin (USAN/INN); Pefloxacin [USAN:BAN:INN]; 1-Ethyl-6-fluoro-1,4-dihydro-4-oxo-7-(4-methyl-1-piperazinyl)-3-quinolinecarboxylic acid; 1-Ethyl-6-fluoro-1,4-dihydro-7-(4-methyl-1-piperazinyl)-4-oxo-3-quinolinecarboxylic acid; 1-ethyl-6-fluoro-7-(4-methyl-1-piperazinyl)-4-oxo-1,4-dihydro-3-quinolinecarboxylic acid; 1-ethyl-6-fluoro-7-(4-methylpiperazin-1-yl)-4-oxo-1,4-dihydroquinoline-3-carboxylic acid; 1-ethyl-6-fluoro-7-(4-methylpiperazin-1-yl)-4-oxoquinoline-3-carboxylic acid; 3-Quinolinecarboxylic acid, 1-ethyl-6-fluoro-1,4-dihydro-7-(4-methyl-1-piperazinyl)-4-oxo
Drug Type
Small molecular drug
Indication Gonococcal urethritis [ICD9: 98; ICD10:A54] Approved [550741]
Therapeutic Class
Antiinfective Agents
Structure
Download
2D MOL

3D MOL

Formula
C17H20FN3O3
Canonical SMILES
CCN1C=C(C(=O)C2=CC(=C(C=C21)N3CCN(CC3)C)F)C(=O)O
InChI
1S/C17H20FN3O3/c1-3-20-10-12(17(23)24)16(22)11-8-13(18)15(9-14(11)20)21-6-4-19(2)5-7-21/h8-10H,3-7H2,1-2H3,(H,23,24)
InChIKey
FHFYDNQZQSQIAI-UHFFFAOYSA-N
CAS Number
CAS 70458-92-3
PubChem Compound ID
PubChem Substance ID
ChEBI ID
ChEBI:50199
SuperDrug ATC ID
J01MA03
SuperDrug CAS ID
cas=070458923
Target and Pathway
Target(s) DNA topoisomerase II Target Info Inhibitor [537741]
References
Ref 550741Drug information of Pefloxacin, 2008. eduDrugs.
Ref 537741Clinical pharmacokinetics of the newer antibacterial 4-quinolones. Clin Pharmacokinet. 1988 Feb;14(2):96-121.

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