Drug Information

Drug General Information
Drug ID
D0X3NW
Former ID
DIB019611
Drug Name
compound 8g
Drug Type
Small molecular drug
Indication Discovery agent Investigative [531413], [541074]
Structure
Download
2D MOL
Formula
C22H26FN5O4S2
InChI
InChI=1S/C22H26FN5O4S2/c1-22(2,3)32-21(29)27-9-7-14(8-10-27)33-20-16-12-26-28(19(16)24-13-25-20)18-6-5-15(11-17(18)23)34(4,30)31/h5-6,11-14H,7-10H2,1-4H3
InChIKey
KRCCTTRJUJRZKA-UHFFFAOYSA-N
PubChem Compound ID
53630410
PubChem Substance ID
127342968, 127342969, 127342970, 131274182, 131346379, 137219002, 139391836, 178102365, 223931686, 226719856, 245461264
Target and Pathway
Target(s) Glucose-dependent insulinotropic receptor Target Info Agonist [531413]
KEGG Pathway cAMP signaling pathway
Insulin secretion
WikiPathways Incretin Synthesis, Secretion, and Inactivation
References
Ref 531413Bioorg Med Chem Lett. 2011 May 15;21(10):3134-41. Epub 2011 Mar 13.Discovery of fused bicyclic agonists of the orphan G-protein coupled receptor GPR119 with in vivo activity in rodent models of glucose control.
Ref 541074(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 5739).
Ref 531413Bioorg Med Chem Lett. 2011 May 15;21(10):3134-41. Epub 2011 Mar 13.Discovery of fused bicyclic agonists of the orphan G-protein coupled receptor GPR119 with in vivo activity in rodent models of glucose control.

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