Drug Information

Drug General Information
Drug ID
D07PSF
Former ID
DIB018901
Drug Name
aspirin triggered lipoxin A4
Synonyms
aspirin-triggered lipoxin A4; ATL; aspirin triggered 15-epi lipoxin A4
Drug Type
Small molecular drug
Indication Discovery agent Investigative [540556]
Structure
Download
2D MOL
Formula
C20H32O5
InChI
InChI=1S/C20H32O5/c1-2-3-8-12-17(21)13-9-6-4-5-7-10-14-18(22)19(23)15-11-16-20(24)25/h4-7,9-10,13-14,17-19,21-23H,2-3,8,11-12,15-16H2,1H3,(H,24,25)/b6-4-,7-5+,13-9+,14-10+/t17-,18-,19+/m1/s1
InChIKey
IXAQOQZEOGMIQS-JEWNPAEBSA-N
PubChem Compound ID
9841438
PubChem Substance ID
14802993, 24139555, 26759063, 44939516, 79177358, 103573272, 135651445, 140337472, 162169222, 163687786, 227876534, 252463293
Target and Pathway
Target(s) FMLP-related receptor I Target Info Agonist [543579]
Pathway Interaction Database Urokinase-type plasminogen activator (uPA) and uPAR-mediated signaling
Reactome G alpha (q) signalling events
G alpha (i) signalling events
WikiPathways GPCRs, Class A Rhodopsin-like
Gastrin-CREB signalling pathway via PKC and MAPK
Peptide GPCRs
GPCR ligand binding
GPCR downstream signaling
References
Ref 540556(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 3933).
Ref 543579(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 223).

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