Drug Information

Drug General Information
Drug ID
D0X7AM
Former ID
DNC005789
Drug Name
SC-0030
Synonyms
SC0030
Drug Type
Small molecular drug
Indication Discovery agent Investigative [467566]
Structure
Download
2D MOL

3D MOL
Formula
C20H26FN3O2S2
InChI
InChI=1S/C20H26FN3O2S2/c1-20(2,3)16-8-5-14(6-9-16)12-22-19(27)23-13-15-7-10-18(17(21)11-15)24-28(4,25)26/h5-11,24H,12-13H2,1-4H3,(H2,22,23,27)
InChIKey
DUHBVFMCIJLUJX-UHFFFAOYSA-N
PubChem Compound ID
10295883
PubChem Substance ID
15302577, 22670514, 35613198, 47583682, 47731181, 49688395, 53786825, 77124961, 103519029, 134342994, 135727747, 137759071, 175427601, 178101047, 198985095, 227496672, 245756233, 252450692, 252543500
Target and Pathway
Target(s) Vanilloid receptor 1 Target Info Inhibitor [530533]
Transient receptor potential cation channel subfamily V member 4 Target Info Inhibitor [526897]
Vanilloid receptor Target Info Inhibitor [530533]
KEGG Pathway Neuroactive ligand-receptor interaction
Inflammatory mediator regulation of TRP channelshsa04750:Inflammatory mediator regulation of TRP channels
NetPath Pathway IL2 Signaling Pathway
Pathway Interaction Database Trk receptor signaling mediated by the MAPK pathway
Trk receptor signaling mediated by PI3K and PLC-gamma
Reactome TRP channelsR-HSA-3295583:TRP channels
References
Ref 467566(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 4230).
Ref 526897Bioorg Med Chem Lett. 2003 Dec 15;13(24):4389-93.Novel non-vanilloid VR1 antagonist of high analgesic effects and its structural requirement for VR1 antagonistic effects.
Ref 530533Bioorg Med Chem. 2010 Jan 1;18(1):111-6. Epub 2009 Nov 10.Silicon switch approach in TRPV1 antagonist MK-056 and its analogues.

If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Zhou and Dr. Zhang.