TTD | Drug: D0L7DL

Drug General Information
Drug ID	D0L7DL
Former ID	DNC006533
Drug Name	8-cyclohexyl-6-(4-tolyl)-2-phenyl-9H-purine
Drug Type	Small molecular drug
Indication	Discovery agent		Investigative	[528192]
Structure		Download 2D MOL 3D MOL
Formula	C24H24N4
Canonical SMILES	CC1=CC=C(C=C1)C2=C3C(=NC(=N2)C4=CC=CC=C4)N=C(N3)C5CCCCC<br />5
InChI	1S/C24H24N4/c1-16-12-14-17(15-13-16)20-21-24(27-22(25-20)18-8-4-2-5-9-18)28-23(26-21)19-10-6-3-7-11-19/h2,4-5,8-9,12-15,19H,3,6-7,10-11H2,1H3,(H,25,26,27,28)
InChIKey	JOTMQRFWDYAWIE-UHFFFAOYSA-N
PubChem Compound ID	11610347
Target and Pathway
Target(s)	Adenosine A1 receptor	Target Info	Inhibitor	[528192]
KEGG Pathway	cGMP-PKG signaling pathway
	cAMP signaling pathway
	Sphingolipid signaling pathway
	Neuroactive ligand-receptor interaction
	Morphine addiction
NetPath Pathway	TCR Signaling Pathway
NetPath Pathway	RANKL Signaling Pathway
PANTHER Pathway	Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway
PANTHER Pathway	Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway
Reactome	Adenosine P1 receptors
Reactome	G alpha (i) signalling events
WikiPathways	Nucleotide GPCRs
	GPCRs, Class A Rhodopsin-like
	GPCR ligand binding
	GPCR downstream signaling
References
Ref 528192	J Med Chem. 2006 May 18;49(10):2861-7.2,6-disubstituted and 2,6,8-trisubstituted purines as adenosine receptor antagonists.
Ref 528192	J Med Chem. 2006 May 18;49(10):2861-7.2,6-disubstituted and 2,6,8-trisubstituted purines as adenosine receptor antagonists.

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Drug Information