Drug Information
Drug General Information | |||||
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Drug ID |
D0RD6G
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Former ID |
DNC007966
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Drug Name |
7-ethynyl-6H-chromeno[4,3-b]quinoline-3,9-diol
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Drug Type |
Small molecular drug
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Indication | Discovery agent | Investigative | [1] | ||
Structure |
Download2D MOL |
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Formula |
C18H11NO3
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Canonical SMILES |
C#CC1=C2COC3=CC(=O)C=CC3=C2NC4=C1C=C(C=C4)O
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InChI |
1S/C18H11NO3/c1-2-12-14-7-10(20)4-6-16(14)19-18-13-5-3-11(21)8-17(13)22-9-15(12)18/h1,3-8,19-20H,9H2
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InChIKey |
KEQHESMVPUELBA-UHFFFAOYSA-N
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PubChem Compound ID | |||||
Target and Pathway | |||||
Target(s) | Steroid hormone receptor ERR1 | Target Info | Inhibitor | [1] | |
Reactome | PPARA activates gene expression | ||||
Transcriptional activation of mitochondrial biogenesis | |||||
Nuclear Receptor transcription pathway | |||||
WikiPathways | Mitochondrial Gene Expression | ||||
Regulation of Lipid Metabolism by Peroxisome proliferator-activated receptor alpha (PPARalpha) | |||||
Nuclear Receptors | |||||
References | |||||
REF 1 | Bioorg Med Chem Lett. 2007 Jul 15;17(14):4053-6. Epub 2007 May 4.ERbeta ligands. Part 6: 6H-Chromeno[4,3-b]quinolines as a new series of estrogen receptor beta-selective ligands. | ||||
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