Drug Information

Drug General Information
Drug ID
D01GPC
Former ID
DIB019539
Drug Name
compound 58
Drug Type
Small molecular drug
Indication Discovery agent Investigative [531346], [541083]
Structure
Download
2D MOL
Formula
C20H25ClN4O3S
InChI
InChI=1S/C20H25ClN4O3S/c1-29(26,27)17-2-3-19(22-13-17)28-9-6-15-10-18(15)14-4-7-25(8-5-14)20-23-11-16(21)12-24-20/h2-3,11-15,18H,4-10H2,1H3/t15-,18-/m1/s1
InChIKey
XFJBGINZIMNZBW-CRAIPNDOSA-N
PubChem Compound ID
53235534
PubChem Substance ID
124344768, 131287857, 131345635, 137273298, 178102374, 227100940, 243747016
Target and Pathway
Target(s) Glucose-dependent insulinotropic receptor Target Info Agonist [531346]
KEGG Pathway cAMP signaling pathway
Insulin secretion
WikiPathways Incretin Synthesis, Secretion, and Inactivation
References
Ref 531346Design of potent and selective GPR119 agonists for type II diabetes. Bioorg Med Chem Lett. 2011 May 1;21(9):2665-9.
Ref 541083(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 5748).
Ref 531346Design of potent and selective GPR119 agonists for type II diabetes. Bioorg Med Chem Lett. 2011 May 1;21(9):2665-9.

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