Drug Information

Drug General Information
Drug ID
D02NMG
Former ID
DPR000107
Drug Name
SLV-332
Drug Type
Small molecular drug
Indication Irritable bowel syndrome [ICD9: 564.1, 787.91; ICD10:A09, K58, K59.1] Preclinical [536224]
Company
Solvay
Structure
Download
2D MOL

3D MOL
Formula
C30H39N3O5S
Canonical SMILES
CC(C)CCOC1=CC=C(C=C1)NC(=S)NC2=CC=C(C=C2)OCCC(C)C.C1=CC<br />(=C(C=C1N)O)C(=O)O
InChI
1S/C23H32N2O2S.C7H7NO3/c1-17(2)13-15-26-21-9-5-19(6-10-21)24-23(28)25-20-7-11-22(12-8-20)27-16-14-18(3)4;8-4-1-2-5(7(10)11)6(9)3-4/h5-12,17-18H,13-16H2,1-4H3,(H2,24,25,28);1-3,9H,8H2,(H,10,11)
InChIKey
HHBOLVQEBVCBNA-UHFFFAOYSA-N
CAS Number
CAS 910-86-1
PubChem Compound ID
3002337
PubChem Substance ID
637391, 34667915, 79275308, 111611645, 134339205, 134339546
SuperDrug ATC ID
J04AD02
SuperDrug CAS ID
cas=000910861
Target and Pathway
Target(s) NK-2 receptor Target Info Antagonist [536224]
KEGG Pathway Calcium signaling pathway
Neuroactive ligand-receptor interaction
Reactome G alpha (q) signalling events
WikiPathways Gastrin-CREB signalling pathway via PKC and MAPK
Peptide GPCRs
GPCR ligand binding
GPCR downstream signaling
References
Ref 536224Emerging drugs for irritable bowel syndrome. Expert Opin Emerg Drugs. 2006 May;11(2):293-313.
Ref 536224Emerging drugs for irritable bowel syndrome. Expert Opin Emerg Drugs. 2006 May;11(2):293-313.

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