TTD | Drug: D0Y2JY

Drug General Information
Drug ID	D0Y2JY
Former ID	DIB019140
Drug Name	CIFEA
Synonyms	cyclohexylmethyl-indenofurane-ethylacetamide
Drug Type	Small molecular drug
Indication	Discovery agent		Investigative	[542732]
Structure		Download 2D MOL
Formula	C22H29NO2
InChI	InChI=1S/C22H29NO2/c1-15(24)23-11-9-19-18(13-16-5-3-2-4-6-16)14-17-7-8-21-20(22(17)19)10-12-25-21/h7-8,16H,2-6,9-14H2,1H3,(H,23,24)
InChIKey	MMMAALHYEKMNHU-UHFFFAOYSA-N
PubChem Compound ID	53238181
PubChem Substance ID	124347536, 131274885, 131346538, 223366113
Target and Pathway
Target(s)	Melatonin receptor	Target Info	Agonist	[531426]
KEGG Pathway	Neuroactive ligand-receptor interaction
KEGG Pathway	Circadian entrainment
Reactome	Class A/1 (Rhodopsin-like receptors)
Reactome	G alpha (i) signalling events
WikiPathways	GPCRs, Class A Rhodopsin-like
	Small Ligand GPCRs
	GPCR ligand binding
	GPCR downstream signaling
References
Ref 542732	(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 7780).
Ref 531426	1,6-Dihydro-2H-indeno[5,4-b]furan derivatives: design, synthesis, and pharmacological characterization of a novel class of highly potent MT??selective agonists. J Med Chem. 2011 May 12;54(9):3436-44.

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Drug Information