Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
D01KAH
|
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| Former ID |
DNC014521
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| Drug Name |
1-[(3-Methoxybenzyl)amino]ethaniminium chloride
|
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| Drug Type |
Small molecular drug
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| Indication | Discovery agent | Investigative | [1] | ||
| Structure |
|
Download2D MOL |
|||
| Formula |
C10H15ClN2O
|
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| Canonical SMILES |
CC(=NCC1=CC(=CC=C1)OC)N.Cl
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| InChI |
1S/C10H14N2O.ClH/c1-8(11)12-7-9-4-3-5-10(6-9)13-2;/h3-6H,7H2,1-2H3,(H2,11,12);1H
|
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| InChIKey |
KAHXLIVOQBJXSB-UHFFFAOYSA-N
|
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| PubChem Compound ID | |||||
| Target and Pathway | |||||
| Target(s) | Nitric-oxide synthase, brain | Target Info | Inhibitor | [1] | |
| BioCyc Pathway | Citrulline-nitric oxide cycle | ||||
| KEGG Pathway | Arginine and proline metabolism | ||||
| Metabolic pathways | |||||
| Calcium signaling pathway | |||||
| Phagosome | |||||
| Circadian entrainment | |||||
| Long-term depression | |||||
| Salivary secretion | |||||
| Alzheimer's disease | |||||
| Amyotrophic lateral sclerosis (ALS) | |||||
| NetPath Pathway | EGFR1 Signaling Pathway | ||||
| PANTHER Pathway | CCKR signaling map ST | ||||
| PathWhiz Pathway | Arginine and Proline Metabolism | ||||
| Reactome | ROS production in response to bacteria | ||||
| Nitric oxide stimulates guanylate cyclase | |||||
| WikiPathways | Monoamine Transport | ||||
| Myometrial Relaxation and Contraction Pathways | |||||
| Amyotrophic lateral sclerosis (ALS) | |||||
| Quercetin and Nf-kB/ AP-1 Induced Cell Apoptosis | |||||
| Spinal Cord Injury | |||||
| Alzheimers Disease | |||||
| Effects of Nitric Oxide | |||||
| Serotonin Transporter Activity | |||||
| References | |||||
| REF 1 | Bioorg Med Chem Lett. 2010 Nov 15;20(22):6495-9. Epub 2010 Sep 17.N-Substituted acetamidines and 2-methylimidazole derivatives as selective inhibitors of neuronal nitric oxide synthase. | ||||
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