Drug General Information
Drug ID
D01WVV
Former ID
DIB018203
Drug Name
[35S]ibutamoren
Synonyms
[35S]MK-0677
Drug Type
Small molecular drug
Indication Discovery agent Investigative [538673]
Structure
Download
2D MOL
Formula
C27H36N4O5S
InChI
InChI=1S/C27H36N4O5S/c1-26(2,28)25(33)29-22(18-36-17-20-9-5-4-6-10-20)24(32)30-15-13-27(14-16-30)19-31(37(3,34)35)23-12-8-7-11-21(23)27/h4-12,22H,13-19,28H2,1-3H3,(H,29,33)/t22-/m1/s1/i37+3
InChIKey
UMUPQWIGCOZEOY-KRTHATKOSA-N
PubChem Compound ID
PubChem Substance ID
Target and Pathway
Target(s) Growth hormone secretagogue receptor type 1 Target Info Agonist [534355]
KEGG Pathway cAMP signaling pathway
Neuroactive ligand-receptor interaction
NetPath Pathway Leptin Signaling Pathway
Reactome Peptide ligand-binding receptors
G alpha (q) signalling events
WikiPathways GPCRs, Class A Rhodopsin-like
Gastrin-CREB signalling pathway via PKC and MAPK
Peptide GPCRs
GPCR ligand binding
GPCR downstream signaling
References
Ref 538673(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 1097).
Ref 534355Molecular analysis of rat pituitary and hypothalamic growth hormone secretagogue receptors. Mol Endocrinol. 1997 Apr;11(4):415-23.

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