Drug General Information
Drug ID
D09DLY
Former ID
DNC008488
Drug Name
1-(3,4-dichlorophenyl)-3-(3,5-dichlorophenyl)urea
Drug Type
Small molecular drug
Indication Discovery agent Investigative [529445]
Structure
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2D MOL

3D MOL

Formula
C13H8Cl4N2O
Canonical SMILES
C1=CC(=C(C=C1NC(=O)NC2=CC(=CC(=C2)Cl)Cl)Cl)Cl
InChI
1S/C13H8Cl4N2O/c14-7-3-8(15)5-10(4-7)19-13(20)18-9-1-2-11(16)12(17)6-9/h1-6H,(H2,18,19,20)
InChIKey
IMDDDJBDFZQNJH-UHFFFAOYSA-N
PubChem Compound ID
Target and Pathway
Target(s) P2Y purinoceptor 1 Target Info Inhibitor [529445]
KEGG Pathway Rap1 signaling pathway
Neuroactive ligand-receptor interaction
Platelet activation
Reactome G alpha (q) signalling events
P2Y receptors
ADP signalling through P2Y purinoceptor 1
WikiPathways Nucleotide GPCRs
GPCRs, Class A Rhodopsin-like
Gastrin-CREB signalling pathway via PKC and MAPK
Signal amplification
GPCR ligand binding
GPCR downstream signaling
References
Ref 529445Bioorg Med Chem Lett. 2008 Jun 1;18(11):3338-43. Epub 2008 Apr 15.P2Y1 receptor antagonists as novel antithrombotic agents.
Ref 529445Bioorg Med Chem Lett. 2008 Jun 1;18(11):3338-43. Epub 2008 Apr 15.P2Y1 receptor antagonists as novel antithrombotic agents.

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