Drug Information

Drug General Information
Drug ID
D0YN8Q
Former ID
DIB021114
Drug Name
UCM 724
Synonyms
UCM-724; UCM724
Drug Type
Small molecular drug
Indication Discovery agent Investigative [542725]
Structure
Download
2D MOL
Formula
C18H20N2O2
InChI
InChI=1S/C18H20N2O2/c1-22-16-7-6-14-8-12-4-2-3-5-13(12)9-15(17(14)10-16)11-20-18(19)21/h2-7,10,15H,8-9,11H2,1H3,(H3,19,20,21)
InChIKey
DIXNMQKCFFPTKU-UHFFFAOYSA-N
PubChem Compound ID
86277838
PubChem Substance ID
223366106
Target and Pathway
Target(s) Melatonin receptor Target Info Antagonist [529075]
KEGG Pathway Neuroactive ligand-receptor interaction
Circadian entrainment
Reactome Class A/1 (Rhodopsin-like receptors)
G alpha (i) signalling events
WikiPathways GPCRs, Class A Rhodopsin-like
Small Ligand GPCRs
GPCR ligand binding
GPCR downstream signaling
References
Ref 542725(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 7773).
Ref 529075Synthesis, enantiomeric resolution, and structure-activity relationship study of a series of 10,11-dihydro-5H-dibenzo[a,d]cycloheptene MT2 receptor antagonists. ChemMedChem. 2007 Dec;2(12):1741-9.

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