Drug Information

Drug General Information
Drug ID
D0QQ7D
Former ID
DAP000926
Drug Name
Tazobactam
Synonyms
TAZ; CL298741; YTR830H; CL-298741; Piprataz (TN); Tazocin (TN); YTR-830H; Zosyn (TN); Tazobactam (JAN/USAN/INN); (2S,3S,5R)-3-methyl-4,4,7-trioxo-3-(triazol-1-ylmethyl)-4; (2S,3S,5R)-3-methyl-7-oxo-3-(1H-1,2,3-triazol-1-ylmethyl)-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid 4,4-dioxide
Drug Type
Small molecular drug
Indication Bacterial infections [ICD9: 001-009, 010-018, 020-027, 030-041, 080-088, 090-099, 100-104; ICD10:A00-B99] Approved [536361]
Therapeutic Class
Antiinfective Agents
Company
Gepach International
Structure
Download
2D MOL

3D MOL
Formula
C10H12N4O5S
Canonical SMILES
CC1(C(N2C(S1(=O)=O)CC2=O)C(=O)O)CN3C=CN=N3
InChI
1S/C10H12N4O5S/c1-10(5-13-3-2-11-12-13)8(9(16)17)14-6(15)4-7(14)20(10,18)19/h2-3,7-8H,4-5H2,1H3,(H,16,17)/t7-,8+,10+/m1/s1
InChIKey
LPQZKKCYTLCDGQ-WEDXCCLWSA-N
CAS Number
CAS 89786-04-9
PubChem Compound ID
123630
PubChem Substance ID
9973, 584542, 604755, 7847726, 7890688, 7980730, 10240806, 14751709, 16012340, 29303858, 46508088, 48416593, 50192512, 90444495, 92711477, 93166370, 103163870, 103949887, 104418948, 126630815, 126657306, 131329684, 134338202, 135693792, 135841765, 137248595, 137981849, 152100220, 160964843, 162009787, 164196449, 175267759, 175607558, 177749299, 179316265, 184544899, 184816524, 196106439, 198993457, 223438269, 223554784, 223684636, 223703155, 224294474, 226493626, 241152814, 249868384, 251912318, 251916632, 252074045
SuperDrug ATC ID
J01CG02
SuperDrug CAS ID
cas=089785842
Target and Pathway
Target(s) Beta-lactamase Target Info Inhibitor [537578]
References
Ref 536361Natural products as sources of new drugs over the last 25 years. J Nat Prod. 2007 Mar;70(3):461-77. Epub 2007 Feb 20.
Ref 537578Selection of TNF-alpha binding affibody molecules using a beta-lactamase protein fragment complementation assay. N Biotechnol. 2009 Jul 1.

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