Drug General Information
Drug ID	D0Y0EK
Former ID	DNC008192
Drug Name	7-hydroxy-2-(3-hydroxyphenyl)chroman-4-one
Drug Type	Small molecular drug
Indication	Discovery agent		Investigative	[529180]
Structure		Download 2D MOL 3D MOL
Formula	C15H12O4
Canonical SMILES	C1C(OC2=C(C1=O)C=CC(=C2)O)C3=CC(=CC=C3)O
InChI	1S/C15H12O4/c16-10-3-1-2-9(6-10)14-8-13(18)12-5-4-11(17)7-15(12)19-14/h1-7,14,16-17H,8H2
InChIKey	MXNJBOFUFMJXOB-UHFFFAOYSA-N
PubChem Compound ID	620596
Target and Pathway
Target(s)	Cytochrome P450 19	Target Info	Inhibitor	[529180]
BioCyc Pathway	Superpathway of steroid hormone biosynthesis
	Estradiol biosynthesis II
	Estradiol biosynthesis I
KEGG Pathway	Steroid hormone biosynthesis
	Metabolic pathways
	Ovarian steroidogenesis
NetPath Pathway	FSH Signaling Pathway
PANTHER Pathway	Androgen/estrogene/progesterone biosynthesis
PathWhiz Pathway	Androgen and Estrogen Metabolism
Reactome	Endogenous sterols
WikiPathways	Metapathway biotransformation
	Tryptophan metabolism
	Oxidation by Cytochrome P450
	Ovarian Infertility Genes
	Metabolism of steroid hormones and vitamin D
	FSH signaling pathway
	Integrated Breast Cancer Pathway
	Phase 1 - Functionalization of compounds
References
Ref 529180	Bioorg Med Chem. 2008 Feb 1;16(3):1474-80. Epub 2007 Oct 22.New 7,8-benzoflavanones as potent aromatase inhibitors: synthesis and biological evaluation.
Ref 529180	Bioorg Med Chem. 2008 Feb 1;16(3):1474-80. Epub 2007 Oct 22.New 7,8-benzoflavanones as potent aromatase inhibitors: synthesis and biological evaluation.

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