Drug General Information
Drug ID	D05MCK
Former ID	DNC003776
Drug Name	7-Chloro-2-phenyl-[1,8]naphthyridin-4-ol
Drug Type	Small molecular drug
Indication	Discovery agent		Investigative	[527090]
Structure		Download 2D MOL 3D MOL
Formula	C14H9ClN2O
Canonical SMILES	C1=CC=C(C=C1)C2=CC(=O)C3=C(N2)N=C(C=C3)Cl
InChI	1S/C14H9ClN2O/c15-13-7-6-10-12(18)8-11(16-14(10)17-13)9-4-2-1-3-5-9/h1-8H,(H,16,17,18)
InChIKey	JSCUNIPKMPNPFX-UHFFFAOYSA-N
PubChem Compound ID	6105572
Target and Pathway
Target(s)	Adenosine A1 receptor	Target Info	Inhibitor	[527090]
KEGG Pathway	cGMP-PKG signaling pathway
	cAMP signaling pathway
	Sphingolipid signaling pathway
	Neuroactive ligand-receptor interaction
	Morphine addiction
NetPath Pathway	TCR Signaling Pathway
	RANKL Signaling Pathway
PANTHER Pathway	Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway
	Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway
Reactome	Adenosine P1 receptors
	G alpha (i) signalling events
WikiPathways	Nucleotide GPCRs
	GPCRs, Class A Rhodopsin-like
	GPCR ligand binding
	GPCR downstream signaling
References
Ref 527090	J Med Chem. 2004 Jun 3;47(12):3019-31.Study on affinity profile toward native human and bovine adenosine receptors of a series of 1,8-naphthyridine derivatives.
Ref 527090	J Med Chem. 2004 Jun 3;47(12):3019-31.Study on affinity profile toward native human and bovine adenosine receptors of a series of 1,8-naphthyridine derivatives.

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