Drug Information
Drug General Information | |||||
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Drug ID |
D00CMV
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Former ID |
DCL000027
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Drug Name |
ABT-102
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Synonyms |
3-(1H-indazol-4-yl)-1-(5-tert-butyl-2,3-dihydro-1H-inden-1-yl)urea
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Drug Type |
Small molecular drug
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Indication | Chronic pathological pain [ICD9: 338,780; ICD10:R52, G89] | Phase 1 | [522601] | ||
Therapeutic Class |
Analgesics
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Company |
Abbott
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Structure |
Download2D MOL |
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Formula |
C21H24N4O
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Canonical SMILES |
CC(C)(C)C1=CC2=C(C=C1)C(CC2)NC(=O)NC3=CC=CC4=C3C=NN4
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InChI |
1S/C21H24N4O/c1-21(2,3)14-8-9-15-13(11-14)7-10-18(15)24-20(26)23-17-5-4-6-19-16(17)12-22-25-19/h4-6,8-9,11-12,18H,7,10H2,1-3H3,(H,22,25)(H2,23,24,26)/t18-/m1/s1
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InChIKey |
TYOYXJNGINZFET-GOSISDBHSA-N
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PubChem Compound ID | |||||
PubChem Substance ID | |||||
Target and Pathway | |||||
Target(s) | Vanilloid receptor 1 | Target Info | Blocker | [537396] | |
NetPath Pathway | IL2 Signaling Pathway | ||||
Pathway Interaction Database | Trk receptor signaling mediated by the MAPK pathway | ||||
Trk receptor signaling mediated by PI3K and PLC-gamma | |||||
Reactome | TRP channels | ||||
References |
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