Drug General Information
Drug ID
D0PJ3M
Former ID
DIB019141
Drug Name
cinnamaldehyde
Synonyms
cinnamic aldehyde
Drug Type
Small molecular drug
Indication Discovery agent Investigative [539553]
Structure
Download
2D MOL
Formula
C9H8O
InChI
InChI=1S/C9H8O/c10-8-4-7-9-5-2-1-3-6-9/h1-8H/b7-4+
InChIKey
KJPRLNWUNMBNBZ-QPJJXVBHSA-N
PubChem Compound ID
PubChem Substance ID
Target and Pathway
Target(s) Transient receptor potential cation channel subfamily V member 3 Target Info Activator [528302]
Transient receptor potential cation channel subfamily A member 1 Target Info Activator [527012]
KEGG Pathway Inflammatory mediator regulation of TRP channelshsa04750:Inflammatory mediator regulation of TRP channels
Reactome TRP channelsR-HSA-3295583:TRP channels
References
Ref 539553(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 2423).
Ref 527012Noxious cold ion channel TRPA1 is activated by pungent compounds and bradykinin. Neuron. 2004 Mar 25;41(6):849-57.
Ref 528302More than cool: promiscuous relationships of menthol and other sensory compounds. Mol Cell Neurosci. 2006 Aug;32(4):335-43. Epub 2006 Jul 7.

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