Drug Information
Drug General Information | |||||
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Drug ID |
D07OVY
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Former ID |
DNC013443
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Drug Name |
5-iodo-1H-indazole
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Drug Type |
Small molecular drug
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Indication | Discovery agent | Investigative | [1] | ||
Structure |
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Download2D MOL |
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Formula |
C7H5IN2
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Canonical SMILES |
C1=CC2=C(C=C1I)C=NN2
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InChI |
1S/C7H5IN2/c8-6-1-2-7-5(3-6)4-9-10-7/h1-4H,(H,9,10)
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InChIKey |
CGCHCLICSHIAAM-UHFFFAOYSA-N
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PubChem Compound ID | |||||
Target and Pathway | |||||
Target(s) | Nitric-oxide synthase, brain | Target Info | Inhibitor | [1] | |
BioCyc Pathway | Citrulline-nitric oxide cycle | ||||
KEGG Pathway | Arginine and proline metabolism | ||||
Metabolic pathways | |||||
Calcium signaling pathway | |||||
Phagosome | |||||
Circadian entrainment | |||||
Long-term depression | |||||
Salivary secretion | |||||
Alzheimer's disease | |||||
Amyotrophic lateral sclerosis (ALS) | |||||
NetPath Pathway | EGFR1 Signaling Pathway | ||||
PANTHER Pathway | CCKR signaling map ST | ||||
PathWhiz Pathway | Arginine and Proline Metabolism | ||||
Reactome | ROS production in response to bacteria | ||||
Nitric oxide stimulates guanylate cyclase | |||||
WikiPathways | Monoamine Transport | ||||
Myometrial Relaxation and Contraction Pathways | |||||
Amyotrophic lateral sclerosis (ALS) | |||||
Quercetin and Nf-kB/ AP-1 Induced Cell Apoptosis | |||||
Spinal Cord Injury | |||||
Alzheimers Disease | |||||
Effects of Nitric Oxide | |||||
Serotonin Transporter Activity | |||||
References | |||||
REF 1 | Bioorg Med Chem Lett. 2007 Jun 1;17(11):3177-80. Epub 2007 Mar 14.4-substituted indazoles as new inhibitors of neuronal nitric oxide synthase. | ||||
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