TTD | Drug: D0G5DH

Drug General Information
Drug ID	D0G5DH
Former ID	DIB019731
Drug Name	diamide 7
Drug Type	Small molecular drug
Indication	Discovery agent		Investigative	[541150]
Structure		Download 2D MOL
Formula	C22H22N2O3S
InChI	InChI=1S/C22H22N2O3S/c1-13-7-6-8-14(2)19(13)23-22(27)20(18-12-11-15(3)28-18)24-21(26)16-9-4-5-10-17(16)25/h4-12,20,25H,1-3H3,(H,23,27)(H,24,26)
InChIKey	AHTURLVFIJHCLS-UHFFFAOYSA-N
PubChem Compound ID	53233899
PubChem Substance ID	124342722, 131279549, 163367358, 178102455
Target and Pathway
Target(s)	FMLP receptor	Target Info	Antagonist	[531432]
KEGG Pathway	Rap1 signaling pathway
	Neuroactive ligand-receptor interaction
	Staphylococcus aureus infection
NetPath Pathway	Leptin Signaling Pathway
PANTHER Pathway	Inflammation mediated by chemokine and cytokine signaling pathway
Pathway Interaction Database	Urokinase-type plasminogen activator (uPA) and uPAR-mediated signaling
Reactome	G alpha (i) signalling events
WikiPathways	GPCRs, Class A Rhodopsin-like
	Human Complement System
	Peptide GPCRs
	GPCR ligand binding
	GPCR downstream signaling
References
Ref 541150	(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 5830).
Ref 531432	Discovery of small molecule human FPR1 receptor antagonists. Bioorg Med Chem Lett. 2011 May 15;21(10):2991-7.

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Drug Information