TTD | Drug: D0ZO8Z

Drug General Information
Drug ID	D0ZO8Z
Former ID	DNC006684
Drug Name	2-(3,4-dimethoxybenzamido)thiophene-3-carboxamide
Drug Type	Small molecular drug
Indication	Discovery agent		Investigative	[528114]
Structure		Download 2D MOL 3D MOL
Formula	C14H14N2O4S
Canonical SMILES	COC1=C(C=C(C=C1)C(=O)NC2=C(C=CS2)C(=O)N)OC
InChI	1S/C14H14N2O4S/c1-19-10-4-3-8(7-11(10)20-2)13(18)16-14-9(12(15)17)5-6-21-14/h3-7H,1-2H3,(H2,15,17)(H,16,18)
InChIKey	LORRZRFBMUDPOE-UHFFFAOYSA-N
PubChem Compound ID	4106590
Target and Pathway
Target(s)	FL cytokine receptor	Target Info	Inhibitor	[528114]
KEGG Pathway	Cytokine-cytokine receptor interaction
	Hematopoietic cell lineage
	Pathways in cancer
	Transcriptional misregulation in cancer
	Acute myeloid leukemia
	Central carbon metabolism in cancer
References
Ref 528114	Bioorg Med Chem Lett. 2006 Jun 15;16(12):3282-6. Epub 2006 Mar 31.Identification of 2-acylaminothiophene-3-carboxamides as potent inhibitors of FLT3.
Ref 528114	Bioorg Med Chem Lett. 2006 Jun 15;16(12):3282-6. Epub 2006 Mar 31.Identification of 2-acylaminothiophene-3-carboxamides as potent inhibitors of FLT3.

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Drug Information