Drug General Information
Drug ID	D0UM4R
Former ID	DNC012199
Drug Name	(2-Chloro-9-methyl-9H-purin-6-yl)-phenyl-amine
Drug Type	Small molecular drug
Indication	Discovery agent		Investigative	[529774]
Structure		Download 2D MOL 3D MOL
Formula	C12H10ClN5
Canonical SMILES	CN1C=NC2=C1N=C(N=C2NC3=CC=CC=C3)Cl
InChI	1S/C12H10ClN5/c1-18-7-14-9-10(16-12(13)17-11(9)18)15-8-5-3-2-4-6-8/h2-7H,1H3,(H,15,16,17)
InChIKey	DBTWDYPKBBODMU-UHFFFAOYSA-N
PubChem Compound ID	15693956
Target and Pathway
Target(s)	Adenosine A1 receptor	Target Info	Inhibitor	[529774]
KEGG Pathway	cGMP-PKG signaling pathway
	cAMP signaling pathway
	Sphingolipid signaling pathway
	Neuroactive ligand-receptor interaction
	Morphine addiction
NetPath Pathway	TCR Signaling Pathway
	RANKL Signaling Pathway
PANTHER Pathway	Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway
	Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway
Reactome	Adenosine P1 receptors
	G alpha (i) signalling events
WikiPathways	Nucleotide GPCRs
	GPCRs, Class A Rhodopsin-like
	GPCR ligand binding
	GPCR downstream signaling
References
Ref 529774	J Med Chem. 1991 Sep;34(9):2877-82.N6,9-disubstituted adenines: potent, selective antagonists at the A1 adenosine receptor.
Ref 529774	J Med Chem. 1991 Sep;34(9):2877-82.N6,9-disubstituted adenines: potent, selective antagonists at the A1 adenosine receptor.

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