Drug Information

Drug General Information
Drug ID
D0Z3NC
Former ID
DIB020013
Drug Name
HPTE
Drug Type
Small molecular drug
Indication Discovery agent Investigative [539869]
Structure
Download
2D MOL
Formula
C14H11Cl3O2
InChI
InChI=1S/C14H11Cl3O2/c15-14(16,17)13(9-1-5-11(18)6-2-9)10-3-7-12(19)8-4-10/h1-8,13,18-19H
InChIKey
IUGDILGOLSSKNE-UHFFFAOYSA-N
PubChem Compound ID
76302
PubChem Substance ID
72994, 1016204, 3319407, 6899674, 7846950, 8038997, 8197949, 16230006, 24879189, 26675696, 26757856, 43131992, 48421831, 48425747, 49762099, 50006164, 50111678, 53790879, 57332052, 77591746, 88312353, 93165540, 93901045, 99259353, 103469394, 104364010, 108145631, 124893080, 124893081, 125501331, 128221295, 135035374, 135162103, 135650353, 137009387, 142411665, 144208934, 144210973, 162230965, 162832024, 163359533, 164836874, 170450980, 172543432, 176322583, 179084086, 184570498, 198979510, 201499775, 223464223
Target and Pathway
Target(s) Estrogen receptor beta Target Info Antagonist [525459]
KEGG Pathway Estrogen signaling pathway
Prolactin signaling pathway
Pathway Interaction Database Plasma membrane estrogen receptor signaling
Validated nuclear estrogen receptor beta network
Validated nuclear estrogen receptor alpha network
Reactome Nuclear Receptor transcription pathway
WikiPathways SIDS Susceptibility Pathways
Ovarian Infertility Genes
Integrated Pancreatic Cancer Pathway
Nuclear Receptors
References
Ref 539869(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 2827).
Ref 525459Signalling by CXC-chemokine receptors 1 and 2 expressed in CHO cells: a comparison of calcium mobilization, inhibition of adenylyl cyclase and stimulation of GTPgammaS binding induced by IL-8 and GROalpha. Br J Pharmacol. 1999 Feb;126(3):810-8.

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